Article
Contrasting morphological changes in PC12 flat cells expressing two different forms of exogenous oncogenic ras.
Experimental cell research - 1 Mar 1994
Rozenberg Y Y, Howard B D
Abstract excerpt
Oncogenic ras is known to transform certain cells, whereas it induces terminal differentiation of others, e.g., neuronal differentiation of PC12 cells. MPT1 is a PC12 flat cell variant that extends glial-like processes and exhibits some properties of noncancer cells in culture, e.g., absence of a...
Topics
- Animals
- Cadmium
- Cell Adhesion
- Cloning, Molecular
- DNA, Neoplasm
- Dexamethasone
- Electrophoresis, Polyacrylamide Gel
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Genetic Variation
- Glial Fibrillary Acidic Protein
- Kirsten murine sarcoma virus
- Lovastatin
- Oncogene Protein p21(ras)
- Oncogene Proteins, Viral
- PC12 Cells
- Phenotype
- Phosphorylation