Article
The induction of ret by Wnt-1 in PC12 cells is atypically dependent on continual Wnt-1 expression.
Oncogene - 1 Feb 1996
Zheng S, Ramachandran B, Haigh J R, Palos T P, Steger K, Howard B D
Abstract excerpt
Wild type PC12 pheochromocytoma cells that had been infected with a Wnt-1-carrying virus and thus express Wnt-1 (PC12/Wnt-1) are known to acquire the same flat cell phenotype as that of spontaneously occurring PC12 flat cell variants except that the latter do not presently express Wnt-1. Flat cell variants of PC12 cells exhibit markedly altered morphology and gene expression. In order to assess the possibility...
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