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Article

Changes in p53 expression can modify cell shape of ras-transformed fibroblasts and epitheliocytes.

Oncogene - 11 Dec 1997

Gloushankova N, Ossovskaya V, Vasiliev J, Chumakov P, Kopnin B

Abstract excerpt

p53 plays an important role in restriction of abnormal cell proliferation. Loss of this safeguard function induced by p53 mutations seems to be a key mechanism in oncogenesis. It cannot be excluded however, that in addition to elimination of p53-dependent checkpoints and/or apoptosis p53 mutations may cause additional effects that contribute to oncogenic transformation. In order to analyse the effects of...

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Identifiers

PMID: 9416842
DOI: 10.1038/sj.onc.1201483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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