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Article

Distinct signaling pathways regulate transformation and inhibition of skeletal muscle differentiation by oncogenic Ras.

Oncogene - 13 Feb 1997

Weyman C M, Ramocki M B, Taparowsky E J, Wolfman A

Abstract excerpt

Expression of oncogenic Ras in 23A2 skeletal myoblasts is sufficient to induce both a transformed phenotype and a differentiation-defective phenotype, but the signaling pathways activated by oncogenic Ras in these cells and their respective contribution to each phenotype have not been explored. In this study, we investigated MAP kinase activity in control 23A2 myoblasts and in 23A2 myoblasts rendered...

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Source

Identifiers

PMID: 9038377
DOI: 10.1038/sj.onc.1200874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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