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Article

A novel gene encoding a B-box protein within the BRCA1 region at 17q21.1.

Human molecular genetics - 1 Apr 1994

Campbell I G, Nicolai H M, Foulkes W D, Senger G, Stamp G W, Allan G, Boyer C, Jones K, Bast R C, Solomon E

Abstract excerpt

A novel cDNA clone was isolated using a polyclonal serum directed against partially purified ovarian carcinoma antigen CA125. The deduced peptide sequence lacked membrane protein characteristics expected for CA125 but encompassed a B-box/coiled coil motif present in many genes with transformation potential. The gene was mapped by fluorescence in situ hybridization within the minimum region known to contain the...

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Source

Identifiers

PMID: 8069304
DOI: 10.1093/hmg/3.4.589

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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A novel gene encoding a B-box protein within the BRCA1 region at 17q21.1.PMID 8069304Read ↗

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High-density genetic map of the BRCA1 region of chromosome 17q12-q21.Semantic proximity Read ↗

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