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Article

Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions.

British journal of cancer - 1 Feb 1999

Catteau A, Xu C F, Brown M A, Hodgson S, Greenman J, Mathew C G, Dunning A M, Solomon E

Abstract excerpt

Reduced expression of BRCA1 has been implicated in sporadic breast cancer, although the mechanisms underlying this phenomenon remain unclear. To determine whether regulatory mutations could account for the reduced expression, we screened the promoter region by sequencing in 20 patients with spora...

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Identifiers

PMID: 10070866
DOI: 10.1038/sj.bjc.6690122
PMCID: PMC2362680

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10070866-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions.PMID 10070866Read ↗

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