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Article

BRCA1 mutations in familial ovarian cancer.

Molecular genetics and metabolism - 1 Aug 1999

Lallas T A, Buekers T E, Buller R E

Abstract excerpt

BRCA1 mutation research in ovarian and breast cancer 17q21-linked families has yielded a large number of germline sequence variations. Somatic mutations have been uncommonly reported. We screened 81 probands with primary ovarian, peritoneal, or fallopian tube carcinoma for BRCA1 mutations. The study group was intentionally biased by the inclusion of 29 probands with a family history of ovarian and/or breast...

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Share to BRCA1 Protein
Share to Chromosomes, Human, Pair 17
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Loss of Heterozygosity

Share to Mutagenesis, Insertional

Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 10444347
DOI: 10.1006/mgme.1999.2871

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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