Article
Sequence analysis of the rat Brca1 homolog and its promoter region.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1999
Bennett L M, Brownlee H A, Hagavik S, Wiseman R W
Abstract excerpt
Since the identification of the human breast and ovarian cancer gene, BRCA1, a large spectrum of germline mutations has been characterized that predispose women to developing these diseases. We have determined the complete coding sequence for the rat BRCA1 homolog and compared it with those of th...
Topics
- Amino Acid Sequence
- Animals
- BRCA1 Protein
- Blotting, Northern
- Conserved Sequence
- Dogs
- Female
- Genetic Variation
- Humans
- Intracellular Signaling Peptides and Proteins
- Mice
- Molecular Sequence Data
- Promoter Regions, Genetic
- Proteins
- Rats
- Rats, Sprague-Dawley
- Sequence Analysis
- Sequence Homology, Amino Acid