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Plasmodium vivax: dimorphic DNA sequences from the MSP-1 gene code for regions that are immunogenic in natural infections.

Experimental parasitology - 1 Sept 1994

Mancilla L I, Levitus G, Kirchgatter K, Mertens F, Herrera S, del Portillo H A

Abstract excerpt

The merozoite surface protein 1 gene of Plasmodium vivax (PvMSP-1) is becoming a solid genetic marker for studying the polymorphism of natural parasite populations from this prevalent human malaria. Indeed, a conserved and a variant PvMSP-1 gene segments have been amplified from total genomic parasite DNA obtained from isolates representing seven countries and three continents. Interestingly, the variant PvMSP-1...

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PMID: 8056078
DOI: 10.1006/expr.1994.1074

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