Allelic diversity at the merozoite surface protein-1 (MSP-1) locus in natural Plasmodium falciparum populations: a brief overview.

doi:10.1590/s0074-02761998000500013

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Article

Allelic diversity at the merozoite surface protein-1 (MSP-1) locus in natural Plasmodium falciparum populations: a brief overview.

Memorias do Instituto Oswaldo Cruz - 1 Jan 2000

Ferreira M U, Kaneko O, Kimura M, Liu Q, Kawamoto F, Tanabe K

Abstract excerpt

The merozoite surface protein-1 (MSP-1) locus of Plasmodium falciparum codes for a major asexual blood-stage antigen currently proposed as a major malaria vaccine candidate. The protein, however, shows extensive polymorphism, which may compromise its use in sub-unit vaccines. Here we compare the...

Topics

Alleles
Animals
Brazil
Endemic Diseases
Genetic Variation
Humans
Malaria, Falciparum
Merozoite Surface Protein 1
Plasmodium falciparum
Tanzania
Vietnam

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