Article
Plasmodium vivax: polymorphism in the merozoite surface protein 1 gene from wild Colombian isolates.
Experimental parasitology - 1 Jul 2000
Gutierrez A, Vicini J, Patarroyo M E, Murillo L A, Patarroyo M A
Abstract excerpt
The Plasmodium vivax merozoite surface protein-1 (PvMSP-1) has been considered a candidate for a malaria vaccine against erythrocytic stages. PvMSP-1 is immunogenic during natural infections and exhibits antigenic polymorphism. The extent of genetic polymorphism in a region between the so-called interspecies conserved blocks (ICBs) 2 and 4 of the PvMSP-1 was analyzed in 20 isolates taken from patients from two...
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