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Article

Near-fixation of a Pfmsp1 block 2 allelic variant in genetically diverse Plasmodium falciparum populations across Western Colombia.

Acta tropica - 1 Apr 2010

Jiménez Judy Natalia, Snounou Georges, Letourneur Frank, Rénia Laurent, Vélez Iván D, Muskus Carlos E

Abstract excerpt

Assessment of the genetic diversity of Plasmodium falciparum in 110 Colombian isolates revealed that nearly all the parasites in the 97 isolates collected in endemic regions west of the Andes shared the same Pfmsp1 block 2 MAD20-type allelic variant, despite showing high diversity for other genetical markers. Analysis of published data indicated that the prevalence of this allelic variant of a major vaccine...

Topics

Alleles
Animals
Colombia
DNA, Protozoan
Gene Frequency
Genetic Variation
Genotype
Humans
Malaria, Falciparum
Merozoite Surface Protein 1
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmodium falciparum

Sequence Analysis, DNA

Source

Identifiers

PMID: 20060375
DOI: 10.1016/j.actatropica.2009.12.009

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