High polymorphism in Plasmodium vivax merozoite surface protein-5 (MSP5).

doi:10.1017/S0031182006001168

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Article

High polymorphism in Plasmodium vivax merozoite surface protein-5 (MSP5).

Parasitology - 1 Dec 2006

Gomez A, Suarez C F, Martinez P, Saravia C, Patarroyo M A

Abstract excerpt

A key issue relating to developing multi-component anti-malarial vaccines, lies in studying Plasmodium vivax surface proteins' genetic variation. The present work was aimed at amplifying, cloning and sequencing the gene encoding P. vivax merozoite surface protein 5 (PvMSP5) in samples obtained from infected patients from Colombian areas having varying malaria transmission rates. Nucleotide sequence data reported...

Topics

Amino Acid Sequence
Animals
Cluster Analysis
Colombia
Genetic Variation
Humans
Malaria, Vivax
Membrane Proteins
Molecular Sequence Data
Plasmodium vivax
Polymerase Chain Reaction
Polymorphism, Genetic
Recombination, Genetic
Selection, Genetic
Sequence Analysis, DNA

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PMID: 16978450
DOI: 10.1017/S0031182006001168

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