Article
Inter-allelic recombination in the Plasmodium vivax merozoite surface protein 1 gene among Indian and Colombian isolates.
Malaria journal - 5 Mar 2004
Maestre Amanda, Sunil Sujatha, Ahmad Gul, Mohmmed Asif, Echeverri Marcela, Corredor Mauricio, Blair Silvia, Chauhan Virander S, Malhotra Pawan
Abstract excerpt
BACKGROUND: A major concern in malaria vaccine development is the polymorphism observed among different Plasmodium isolates in different geographical areas across the globe. The merozoite surface protein 1 (MSP-1) is a leading vaccine candidate antigen against asexual blood stages of malaria parasite. To date, little is known about the extent of sequence variation in the Plasmodium vivax MSP-1 gene (Pvmsp-1)...
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