Article
Genetic diversity and selection in three Plasmodium vivax merozoite surface protein 7 (Pvmsp-7) genes in a Colombian population.
PloS one - 1 Jan 2012
Garzón-Ospina Diego, López Carolina, Forero-Rodríguez Johanna, Patarroyo Manuel A
Abstract excerpt
A completely effective vaccine for malaria (one of the major infectious diseases worldwide) is not yet available; different membrane proteins involved in parasite-host interactions have been proposed as candidates for designing it. It has been found that proteins encoded by the merozoite surface protein (msp)-7 multigene family are antibody targets in natural infection; the nucleotide diversity of three Pvmsp-7...
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