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Article

Merozoite surface protein-1 genetic diversity in Plasmodium malariae and Plasmodium brasilianum from Brazil.

BMC infectious diseases - 16 Nov 2015

Guimarães Lilian O, Wunderlich Gerhard, Alves João M P, Bueno Marina G, Röhe Fabio, Catão-Dias José L, Neves Amanda, Malafronte Rosely S, Curado Izilda, Domingues Wilson, Kirchgatter Karin

Abstract excerpt

BACKGROUND: The merozoite surface protein 1 (MSP1) gene encodes the major surface antigen of invasive forms of the Plasmodium erythrocytic stages and is considered a candidate vaccine antigen against malaria. Due to its polymorphisms, MSP1 is also useful for strain discrimination and consists of a good genetic marker. Sequence diversity in MSP1 has been analyzed in field isolates of three human parasites: P....

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PMID: 26572971
DOI: 10.1186/s12879-015-1238-8
PMCID: PMC4647813

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