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Article

Restricted genetic diversity of Plasmodium falciparum major merozoite surface protein 1 in isolates from Colombia.

The American journal of tropical medicine and hygiene - 1 Nov 2005

Terrientes Zilka I, Vergara Juana, Kramer Kenton, Herrera Sócrates, Chang Sandra P

Abstract excerpt

The merozoite surface protein 1 (MSP-1) gene of Plasmodium falciparum encodes a major immune target under development as a malaria vaccine. In this study, we typed MSP-1 variable regions of parasites obtained from Buenaventura, Colombia. Four MSP-1 gene types were detected corresponding to prototype and recombinant K1 and MAD20 block 4 sequences. In contrast to variability within block 4, blocks 2, 6, and 16-17...

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Identifiers

PMID: 16291768
DOI: 10.4269/ajtmh.2005.73.55

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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