Article
Only wild-type c-Ki-ras codons 12, 13, and 61 in human pancreatic acinar cell carcinomas.
Molecular carcinogenesis - 1 Jun 1994
Terhune P G, Heffess C S, Longnecker D S
Abstract excerpt
Activation of the c-Ki-ras proto-oncogene is more common in carcinomas of the pancreas than in other human carcinomas. Most such carcinomas are of the ductal cell phenotype. Ductal adenocarcinomas of the hamster pancreas have similar mutations, but acinar cell carcinomas of the mouse and rat pancreas lack the common c-Ki-ras mutations. Therefore, we examined 11 acinar cell carcinomas of the human pancreas for...
Topics
- Alleles
- Base Sequence
- Carcinoma, Acinar Cell
- Codon
- Formaldehyde
- Gene Expression Regulation, Neoplastic
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Pancreatic Neoplasms