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Article

Activation of c-Ki-ras not detectable in adenomas or adenocarcinomas arising in rat pancreas.

Molecular carcinogenesis - 1 Jan 1990

Schaeffer B K, Zurlo J, Longnecker D S

Abstract excerpt

The objective of this study was to determine whether activation of c-Ki-ras occurs in carcinogen-induced rat pancreatic tumors. DNAs from 27 samples, which included adenomas, carcinomas in situ, and adenocarcinomas arising in azaserine-treated rats and corn oil-gavaged rats along with a nafenopin-induced rat pancreatic adenocarcinoma were examined for mutation of c-Ki-ras at codons 12, 13, and 61 by using the...

Topics

Adenocarcinoma
Adenoma
Animals
Gene Expression Regulation
Genes, ras
Male
Mutation
Pancreatic Neoplasms
Polymerase Chain Reaction
Rats
Rats, Inbred F344
Rats, Inbred Lew

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2196902
DOI: 10.1002/mc.2940030310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2196902-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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