Article
Ki-ras mutations in exocrine pancreatic cancer: association with clinico-pathological characteristics and with tobacco and alcohol consumption. PANK-ras I Project Investigators.
International journal of cancer - 17 Mar 1997
Malats N, Porta M, Corominas J M, Piñol J L, Rifà J, Real F X
Abstract excerpt
The aims of this study were (i) to assess the prevalence and spectrum of codon 12 Ki-ras mutations in patients diagnosed with exocrine pancreatic cancer (EPC) in 2 general hospitals between 1980 and 1990, (ii) to analyze the association of this genetic alteration with clinical and pathological characteristics, and (iii) to determine the association of Ki-ras mutations with tobacco and alcohol consumption. DNA was...
Topics
- Adult
- Aged
- Alcohol Drinking
- Amino Acid Sequence
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
- Logistic Models
- Male
- Middle Aged
- Mutation
- Neoplasm Metastasis
- Pancreatic Neoplasms