Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of c-K-ras in pancreatic carcinomas from Ela-1, SV40E transgenic mice.

Carcinogenesis - 1 Dec 1993

Kuhlmann E, Terhune P G, Longnecker D S

Abstract excerpt

c-K-ras is activated by mutation at codon 12 in the majority of human pancreatic carcinomas of ductal, but not acinar, phenotype. Therefore, evaluation of c-K-ras in experimentally induced pancreatic carcinomas in animal models is of interest for comparison with the human disease. Acinar cell carcinomas and islet cell tumors arising in two strains of transgenic mice carrying the Ela-1-SV40E transgene were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pancreatic Neoplasms
Share to Disease Models, Animal
Share to Genes, ras

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8269641
DOI: 10.1093/carcin/14.12.2649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of c-K-ras in pancreatic carcinomas from Ela-1, SV40E transgenic mice.PMID 8269641Read ↗

Pancreatic carcinomas of acinar and mixed acinar/ductal phenotypes in Ela-1-myc transgenic mice do not contain c-K-ras mutations.Semantic proximity Read ↗

Only wild-type c-Ki-ras codons 12, 13, and 61 in human pancreatic acinar cell carcinomas.Semantic proximity Read ↗

High yields of K-ras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine in the pancreas of female Syrian hamsters.Semantic proximity Read ↗

Evaluation of p53 mutation in pancreatic acinar cell carcinomas of humans and transgenic mice.Semantic proximity Read ↗

Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.Semantic proximity Read ↗

Activation of c-K-ras is frequent in pancreatic carcinomas of Syrian hamsters, but is absent in pancreatic tumors of rats.Semantic proximity Read ↗

Molecular differences between human and experimental pancreaticobiliary diversion-induced rat pancreatic neoplasia.Semantic proximity Read ↗

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.Semantic proximity Read ↗

Detection of codon 12 mutation in the K-ras oncogene in pancreatic tumors.Semantic proximity Read ↗

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing.Semantic proximity Read ↗

Mutational activation of the c-K-ras gene in human pancreatic carcinoma.Semantic proximity Read ↗

Characterization of the ELSV transgenic mouse model of pancreatic carcinoma. Histologic type of large and small tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.