Evaluation of c-K-ras in pancreatic carcinomas from Ela-1, SV40E transgenic mice.

doi:10.1093/carcin/14.12.2649

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Article

Evaluation of c-K-ras in pancreatic carcinomas from Ela-1, SV40E transgenic mice.

Carcinogenesis - 1 Dec 1993

Kuhlmann E, Terhune P G, Longnecker D S

Abstract excerpt

c-K-ras is activated by mutation at codon 12 in the majority of human pancreatic carcinomas of ductal, but not acinar, phenotype. Therefore, evaluation of c-K-ras in experimentally induced pancreatic carcinomas in animal models is of interest for comparison with the human disease. Acinar cell car...

Topics

Animals
Disease Models, Animal
Female
Genes, ras
Male
Mice
Mice, Transgenic
Mutation
Pancreatic Neoplasms
Polymerase Chain Reaction

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