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Article

KRAS Mutations in Canine and Feline Pancreatic Acinar Cell Carcinoma.

Journal of comparative pathology - 1 Jul 2016

Crozier C, Wood G A, Foster R A, Stasi S, Liu J H W, Bartlett J M S, Coomber B L, Sabine V S

Abstract excerpt

Companion animals may serve as valuable models for studying human cancers. Although KRAS is the most commonly mutated gene in human ductal pancreatic cancers (57%), with mutations frequently occurring at codons 12, 13 and 61, human pancreatic acinar cell carcinomas (ACCs) lack activating KRAS mutations. In the present study, 32 pancreatic ACC samples obtained from 14 dogs and 18 cats, including seven metastases,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27290644
DOI: 10.1016/j.jcpa.2016.05.007

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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