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Article

Ki-ras oncogene activation in preinvasive pancreatic cancer.

Gastroenterology - 1 Jan 1992

Lemoine N R, Jain S, Hughes C M, Staddon S L, Maillet B, Hall P A, Klöppel G

Abstract excerpt

Activation of the Ki-ras oncogene by specific point mutations at codon 12 occurs at a remarkably high frequency in pancreatic ductal adenocarcinoma and is likely to be an important event in the pathogenesis of this cancer. To determine whether ras activation also occurs in noninvasive proliferati...

Topics

Adult
Aged
Carcinoma, Intraductal, Noninfiltrating
Female
Gene Expression Regulation, Neoplastic
Genes, ras
Humans
Hyperplasia
Male
Middle Aged
Mutation
Neoplasm Invasiveness
Oncogenes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic Ducts

Pancreatic Neoplasms

Source

Identifiers

PMID: 1309358
DOI: 10.1016/0016-5085(92)91805-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1309358-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Ki-ras oncogene activation in preinvasive pancreatic cancer.PMID 1309358Read ↗

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