Article
Primary Sex Determination in Drosophila melanogaster Does Not Rely on the Male-Specific Lethal Complex.
Genetics - 1 Feb 2016
Erickson James W
Abstract excerpt
It has been proposed that the Male Specific Lethal (MSL) complex is active in Drosophila melanogaster embryos of both sexes prior to the maternal-to-zygotic transition. Elevated gene expression from the two X chromosomes of female embryos is proposed to facilitate the stable establishment of Sex-lethal (Sxl) expression, which determines sex and represses further activity of the MSL complex, leaving it active only...
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