Article
Histone acetylation and gene expression analysis of sex lethal mutants in Drosophila.
Genetics - 1 Jun 2000
Bhadra U, Pal-Bhadra M, Birchler J A
Abstract excerpt
The evolution of sex determination mechanisms is often accompanied by reduction in dosage of genes on a whole chromosome. Under these circumstances, negatively acting regulatory genes would tend to double the expression of the genome, which produces compensation of the single-sex chromosome and increases autosomal gene expression. Previous work has suggested that to reduce the autosomal expression to the female...
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