Genetic and molecular analysis of new female-specific lethal mutations at the gene Sxl of Drosophila melanogaster.

doi:10.1093/genetics/129.2.371

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetic and molecular analysis of new female-specific lethal mutations at the gene Sxl of Drosophila melanogaster.

Genetics - 1 Oct 1991

Granadino B, Torres M, Bachiller D, Torroja E, Barbero J L, Sánchez L

Abstract excerpt

We have isolated three female-specific lethal mutations at the gene Sex-lethal (Sxl): Sxlfb, Sxlfc and Sxlfd. We have carried out the complementation analysis between these mutations and other previously reported Sxlf mutations. It is possible to classify the alleles tested in this report into two complementation groups: the bc group defined by Sxlfb, and Sxlfc, and the LS group defined by SxlfLS. The other...

Topics

Alleles
Animals
Blotting, Southern
Dosage Compensation, Genetic
Drosophila melanogaster
Ethyl Methanesulfonate
Female
Fertility
Genes, Lethal
Genetic Complementation Test
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mutation

Oogenesis

Restriction Mapping

Sex Differentiation

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1743482
DOI: 10.1093/genetics/129.2.371
PMCID: PMC1204630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1743482-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and molecular analysis of new female-specific lethal mutations at the gene Sxl of Drosophila melanogaster.PMID 1743482Read ↗

Differential effects of Sex-lethal mutations on dosage compensation early in Drosophila development.Semantic proximity Read ↗

The Drosophila melanogaster fl(2)d gene is needed for the female-specific splicing of Sex-lethal RNA.Semantic proximity Read ↗

An N-terminal truncation uncouples the sex-transforming and dosage compensation functions of sex-lethal.Semantic proximity Read ↗

Evidence of a dual function in fl(2)d, a gene needed for Sex-lethal expression in Drosophila melanogaster.Semantic proximity Read ↗

Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.Semantic proximity Read ↗

Evolution of the Drosophila feminizing switch gene Sex-lethal.Semantic proximity Read ↗

Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis.Semantic proximity Read ↗

Genetic and molecular analysis of the autosomal component of the primary sex determination signal of Drosophila melanogaster.Semantic proximity Read ↗

sisterless A is required for activation of Sex lethal in the Drosophila germlineSemantic proximity Read ↗

flex, an X-linked female-lethal mutation in Drosophila melanogaster controls the expression of Sex-lethal.Semantic proximity Read ↗

Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product.Semantic proximity Read ↗

Transposon insertions causing constitutive Sex-lethal activity in Drosophila melanogaster affect Sxl sex-specific transcript splicing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.