Article
Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease.
The American journal of pathology - 1 Dec 1994
Harrington C R, Louwagie J, Rossau R, Vanmechelen E, Perry R H, Perry E K, Xuereb J H, Roth M, Wischik C M
Abstract excerpt
Alzheimer's disease (AD) is associated with an increased frequency of the apolipoprotein E type epsilon 4 allele. To address both the disease and the allele specificity of this association, we have examined the apolipoprotein E allele distribution in 255 elderly persons including those with autop...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Amyloid beta-Peptides
- Apolipoproteins E
- Dementia, Vascular
- Female
- Genotype
- Homozygote
- Humans
- Huntington Disease
- Immunochemistry
- Male