Article
Effects of apolipoprotein E genotype on cortical neuropathology in senile dementia of the Lewy body and Alzheimer's disease.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration - 1 Dec 1995
Benjamin R, Leake A, Ince P G, Perry R H, McKeith I G, Edwardson J A, Morris C M
Abstract excerpt
Apolipoprotein E (APO E) genotypes were determined in a UK population of neuropathologically confirmed control cases, and in cases of Lewy body dementia (SDLT) and late onset Alzheimer's disease (AD). APO E epsilon 4 allele frequency was significantly elevated in both SDLT and AD groups with a concomitant reduction in the APO E epsilon 3 allele frequency. The epsilon 2 allele frequency in the AD group was only...
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