Article
Effects of apolipoprotein E genotype on cortical neuropathology in senile dementia of the Lewy body and Alzheimer's disease.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration - 1 Dec 1995
Benjamin R, Leake A, Ince P G, Perry R H, McKeith I G, Edwardson J A, Morris C M
Abstract excerpt
Apolipoprotein E (APO E) genotypes were determined in a UK population of neuropathologically confirmed control cases, and in cases of Lewy body dementia (SDLT) and late onset Alzheimer's disease (AD). APO E epsilon 4 allele frequency was significantly elevated in both SDLT and AD groups with a co...
Topics
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Base Sequence
- Case-Control Studies
- Cerebral Cortex
- Dementia
- Gene Frequency
- Genotype
- Humans
- Molecular Sequence Data
- Parkinson Disease