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Article

Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies.

Annals of neurology - 1 Dec 1994

Nalbantoglu J, Gilfix B M, Bertrand P, Robitaille Y, Gauthier S, Rosenblatt D S, Poirier J

Abstract excerpt

Apoliprotein E (apoE) is associated with Alzheimer's neurofibrillary tangles and beta-amyloid protein in senile plaques. Recent studies have shown an increased frequency of the epsilon 4 allele of the apoE gene in familial and sporadic cases of Alzheimer's disease (AD). In the present case control study, we have determined the apoE genotype by allele-specific extension of 113 postmortem cases of sporadic AD and...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
Apolipoproteins E
Autopsy
Base Sequence
Case-Control Studies
Female
Genotype
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Molecular Sequence Data

Predictive Value of Tests

Source

Identifiers

PMID: 7998776
DOI: 10.1002/ana.410360614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7998776-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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