A mutant v-rel with increased ability to transform B lymphocytes.

doi:10.1128/JVI.69.1.301-307.1995

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Article

A mutant v-rel with increased ability to transform B lymphocytes.

Journal of virology - 1 Jan 1995

Romero P, Humphries E H

Abstract excerpt

We observed that two strains of REV-T differ in the ability to transform bursal cells in vitro. REV-TW, with v-rel derived from a well-characterized clone and considered the prototype of the wild type, fails to generate colonies in soft agar. In contrast, REV-S2A3, derived from the S2A3 cell line...

Topics

Alanine
Amino Acid Sequence
Animals
B-Lymphocytes
Base Sequence
Cell Line
Cell Transformation, Neoplastic
Chickens
DNA Primers
DNA-Binding Proteins
Molecular Sequence Data
Mutation
Oncogene Proteins v-rel
Retroviridae Proteins, Oncogenic
Serine

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