Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus.

doi:10.1101/gad.8.16.1949

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Article

Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus.

Genes & development - 15 Aug 1994

Spyropoulos D D, Capecchi M R

Abstract excerpt

Implantation within the mammalian uterus elicits dramatic changes in the growth, differentiation, and morphogenesis of the conceptus. This process is interrupted in mice carrying a targeted disruption of the murine evx1 gene, a homolog of the Drosophila even-skipped (eve) gene. Upon implantation,...

Topics

Animals
Base Sequence
Crosses, Genetic
DNA Primers
Drosophila
Embryo Implantation
Embryo Loss
Embryonic and Fetal Development
Female
Gene Expression Regulation, Developmental
Genes, Homeobox
Genes, Insect
Genes, Lethal
Genetic Vectors
In Situ Hybridization
Male
Mice
Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7958869
DOI: 10.1101/gad.8.16.1949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7958869-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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