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Article

Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth.

Nature genetics - 1 Nov 1998

Li Y, Behringer R R

Abstract excerpt

In marsupials and mice, the paternally derived X chromosome is preferentially inactivated in the placental tissues of female embryos. We show here that the X-linked homeobox gene Esx1 (refs 5,6), whose expression is restricted to extraembryonic tissues, is a chromosomally imprinted regulator of placental morphogenesis and trophoblast differentiation. Heterozygous female mice that inherited a mutant Esx1 allele...

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PMID: 9806555
DOI: 10.1038/3129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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