Article
Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth.
Nature genetics - 1 Nov 1998
Li Y, Behringer R R
Abstract excerpt
In marsupials and mice, the paternally derived X chromosome is preferentially inactivated in the placental tissues of female embryos. We show here that the X-linked homeobox gene Esx1 (refs 5,6), whose expression is restricted to extraembryonic tissues, is a chromosomally imprinted regulator of p...
Topics
- Animals
- Crosses, Genetic
- Embryonic and Fetal Development
- Female
- Fetal Growth Retardation
- Genetic Linkage
- Genomic Imprinting
- Heterozygote
- Homeodomain Proteins
- Homozygote
- Humans
- Mice
- Mutation
- Phenotype
- Placentation
- Pregnancy
- Proto-Oncogene Proteins
- Transcription Factors