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Article

Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan.

Circulation research - 25 Nov 2005

Fujioka Miki, Wessells Robert J, Han Zhe, Liu Jiandong, Fitzgerald Kerry, Yusibova Galina L, Zamora Monica, Ruiz-Lozano Pilar, Bodmer Rolf, Jaynes James B

Abstract excerpt

The Drosophila pair-rule gene even skipped (eve) is required for embryonic segmentation and later in specific cell lineages in both the nervous system and the mesoderm. We previously generated eve mesoderm-specific mutants by combining an eve null mutant with a rescuing transgene that includes the entire locus, but with the mesodermal enhancer removed. This allowed us to analyze in detail the defects that result...

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Identifiers

PMID: 16239588
DOI: 10.1161/01.RES.0000191546.08532.B2
PMCID: PMC2726805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan.PMID 16239588Read ↗

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Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites.Semantic proximity Read ↗

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