Article
Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression.
Development (Cambridge, England) - 1 Sept 1996
Benson G V, Lim H, Paria B C, Satokata I, Dey S K, Maas R L
Abstract excerpt
The establishment of a receptive uterine environment is critical for embryonic survival and implantation. One gene that is expressed in the uterus during the peri-implantation period in mice and is required for female fertility is the homeobox gene Hoxa-10. Here we characterize the peri-implantat...
Topics
- Animals
- DNA-Binding Proteins
- Embryo Implantation
- Embryo Loss
- Embryo Transfer
- Embryonic and Fetal Development
- Female
- Fertility
- Genes, Homeobox
- Genitalia, Female
- Genitalia, Male
- Homeobox A10 Proteins
- Homeodomain Proteins
- In Situ Hybridization
- Infertility
- Male
- Mice
- Mice, Transgenic