Article
Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10.
Molecular and cellular biology - 1 Jan 2003
Troy Patrick J, Daftary Gaurang S, Bagot Catherine N, Taylor Hugh S
Abstract excerpt
HOXA10 is necessary for mammalian reproduction; however, its transcriptional targets are not completely defined. EMX2, a divergent homeobox gene, is necessary for urogenital tract development. In these studies we identify and characterize the regulation of EMX2 by HOXA10. By using Northern analysis and in situ hybridization, we found that EMX2 is expressed in the adult urogenital tract in an inverse temporal...
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