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Article

Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2004

Okita Keisuke, Kiyonari Hiroshi, Nobuhisa Ikuo, Kimura Naoki, Aizawa Shinichi, Taga Tetsuya

Abstract excerpt

Early mouse development is a complicated process that is controlled by various proteins including transcription factors. Recently, we identified a putative transcription factor, ELYS (embryonic large molecule derived from yolk sac), using a subtraction strategy. To elucidate the role of ELYS in vivo, we generated ELYS-deficient mice by homologous recombination. Although heterozygous mice appeared to be healthy,...

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PMID: 15507119
DOI: 10.1111/j.1365-2443.2004.00791.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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