Article
Sox17 is essential for proper formation of the marginal zone of extraembryonic endoderm adjacent to a developing mouse placental disk.
Biology of reproduction - 1 Sept 2018
Igarashi Hitomi, Uemura Mami, Hiramatsu Ryuji, Hiramatsu Ryuto, Segami Saki, Pattarapanawan Montri, Hirate Yoshikazu, Yoshimura Yuki, Hashimoto Haruo, Higashiyama Hiroki, Sumitomo Hiroyuki, Kurohmaru Masamichi, Saijoh Yukio, Suemizu Hiroshi, Kanai-Azuma Masami, Kanai Yoshiakira
Abstract excerpt
In mouse conceptus, two yolk-sac membranes, the parietal endoderm (PE) and visceral endoderm (VE), are involved in protecting and nourishing early-somite-stage embryos prior to the establishment of placental circulation. Both PE and VE membranes are tightly anchored to the marginal edge of the developing placental disk, in which the extraembryonic endoderm (marginal zone endoderm: ME) shows the typical flat...
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