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Article

Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele.

Annals of neurology - 1 Feb 2002

Mori Etsuro, Lee KangUk, Yasuda Minoru, Hashimoto Mamoru, Kazui Hiroaki, Hirono Nobutsugu, Matsui Mieko

Abstract excerpt

Although apolipoprotein E epsilon4 is an established risk factor for Alzheimer's disease, its effect on the rate of progression of Alzheimer's disease remains unknown. The purpose of this longitudinal study was to elucidate whether the rate of hippocampal atrophy is a function of the apolipoprotein E genotypes and severity of disease. Fifty-five patients with probable Alzheimer's disease were the subjects. The...

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Identifiers

PMID: 11835377
DOI: 10.1002/ana.10093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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