Article
Epsilon 4 allele of apolipoprotein E increases risk of Alzheimer's disease in a Chinese population.
Neurology - 1 Jun 1996
Hong C J, Liu T Y, Liu H C, Wang S J, Fuh J L, Chi C W, Lee K Y, Sim C B
Abstract excerpt
We examined the apolipoprotein E genotype in 56 Chinese patients with late-onset sporadic Alzheimer's disease (AD) and 57 Chinese control subjects of similar age. The frequency of epsilon 4 in the AD group was significantly higher than that in the control group (23.2% versus 7.9%, p = 0.003). The odds ratio for AD in individuals with either one or two epsilon 4 was 2.96 (95% CI 1.11 to 8.03). The linear trend for...
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