Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans.

doi:10.1016/s0304-3940(99)00867-8

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Article

Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans.

Neuroscience letters - 31 Dec 1999

Kim K W, Jhoo J H, Lee K U, Lee D Y, Lee J H, Youn J Y, Lee B J, Han S H, Woo J I

Abstract excerpt

We analyzed the aplolipoprotein E (APOE) genotypes of 110 probable AD patients and 226 cognitively normal controls in Koreans. The APOE epsilon4 allele was more prevalent in both early- and late-onset AD patients (P < 0.01) than in controls. The odds for the APOE epsilon4-heterozygous subjects we...

Topics

Age of Onset
Aged
Aged, 80 and over
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Asian People
Female
Gene Frequency
Genotype
Heterozygote
Homozygote
Humans
Korea
Male
Middle Aged
Polymorphism, Genetic
Reference Values

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