Article
Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans.
Neuroscience letters - 31 Dec 1999
Kim K W, Jhoo J H, Lee K U, Lee D Y, Lee J H, Youn J Y, Lee B J, Han S H, Woo J I
Abstract excerpt
We analyzed the aplolipoprotein E (APOE) genotypes of 110 probable AD patients and 226 cognitively normal controls in Koreans. The APOE epsilon4 allele was more prevalent in both early- and late-onset AD patients (P < 0.01) than in controls. The odds for the APOE epsilon4-heterozygous subjects were 2.7 (95% CI = 1.6-4.5), and those for the APOE epsilon4-homozygous subjects were 17.4 (95% CI = 2.0-147.3). But the...
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