Article
[Apolipoprotein E genotype as a risk factor in Japanese patients with early-onset and late-onset Alzheimer's disease].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica - 1 Jan 1997
Shimada K, Yasuda M, Maeda K
Abstract excerpt
Recent studies have provided evidence of an association of apolipoprotein E (apoE) epsilon 4 allele and late-onset sporadic Alzheimer's disease (AD). Some studies have shown the possibility that apoE epsilon 4 is a risk factor of developing AD in early-onset type. We have analyzed the apoE gene polymorphism in a sample of 310 Japanese AD subjects and 237 age-matched Japanese controls. We divided the sporadic AD...
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