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Article

Accumulation of nuclear p53 and tumor progression in bladder cancer.

The New England journal of medicine - 10 Nov 1994

Esrig D, Elmajian D, Groshen S, Freeman J A, Stein J P, Chen S C, Nichols P W, Skinner D G, Jones P A, Cote R J

Abstract excerpt

BACKGROUND: We have previously demonstrated a strong association between nuclear accumulation of p53 protein, as determined by immunohistochemical analysis, and mutations in the p53 gene. The purpose of this study was to determine the relation between nuclear accumulation of p53 and tumor progression in transitional-cell carcinoma of the bladder. METHODS: Histologic specimens of transitional-cell carcinoma of the...

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Source

Identifiers

PMID: 7935683
DOI: 10.1056/NEJM199411103311903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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