Article
The predictive value of p53, p27(kip1), and alpha-catenin for progression in superficial bladder carcinoma.
European urology - 1 Jul 2006
Schrier Barthold Ph, Vriesema Jessica L J, Witjes J Alfred, Kiemeney Lambertus A L M, Schalken Jack A
Abstract excerpt
OBJECTIVE: The aim of the study was to confirm the predictive value of cell cycle regulatory proteins, p53 and p27(kip1), and the cell adhesion complex protein alpha-catenin, for progression in patients with superficial bladder carcinoma. METHODS: Forty-one patients with progression after primary superficial bladder carcinoma were individually matched to patients with nonprogressive superficial bladder carcinoma....
Topics
- Cyclin-Dependent Kinase Inhibitor p27
- Disease Progression
- Humans
- Immunohistochemistry
- Mutation
- Neoplasm Invasiveness
- Tumor Suppressor Protein p53
- Urinary Bladder Neoplasms
- alpha Catenin
