Article
Prognostic implications of p53 gene mutations in bladder tumors.
The Journal of urology - 1 Feb 2003
Lorenzo-Romero J G, Salinas-Sánchez A S, Giménez-Bachs J M, Sánchez-Sánchez F, Escribano-Martínez J, Segura-Martín M, Hernandez-Millán I R, Virseda-Rodríguez J A
Abstract excerpt
PURPOSE: Alterations in the p53 gene related to neoplastic progression were studied in tumor tissue samples from patients with transitional cell carcinoma and correlated with classic staging parameters. On this basis, biological characterization of the tumor was performed to establish subgroups of patients at high risk and those with a more favorable prognosis. MATERIALS AND METHODS: This observational,...
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