Article
Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: a long-term study.
Urologic oncology - 1 Jan 2000
Salinas-Sánchez Antonio S, Lorenzo-Romero Juan G, Giménez-Bachs José M, Sánchez-Sánchez Francisco, Donate-Moreno María J, Rubio-Del-Campo Antonio, Hernández-Millán Ibrahim R, Segura-Martín Miguel, Atienzar-Tobarra Manuel, Escribano-Martínez Julio
Abstract excerpt
OBJECTIVE: To determine the prognostic value of p53 gene mutations and P53 overexpression for predicting the incidence of recurrence, progression and long-term survival of patients with transitional cell carcinoma (TCC) of the bladder. METHODS: Prospective cohort study with 94 consecutive patients diagnosed and treated for TCC. DNA was obtained from tumor tissue to perform PCR-SSCP of p53 exons 5-9, with...
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