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Article

p53 gene and protein status: the role of p53 alterations in predicting outcome in patients with bladder cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2007

George Ben, Datar Ram H, Wu Lin, Cai Jie, Patten Nancy, Beil Stephen J, Groshen Susan, Stein John, Skinner Donald, Jones Peter A, Cote Richard J

Abstract excerpt

PURPOSE: The p53 gene status (mutation) and protein alterations (nuclear accumulation detectable by immunohistochemistry; p53 protein status) are associated with bladder cancer progression. Substantial discordance is documented between the p53 protein and gene status, yet no studies have examined the relationship between the gene-protein status and clinical outcome. This study evaluated the clinical relationship...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18048815
DOI: 10.1200/JCO.2006.10.4125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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