Evaluation of overexpression of p53 tumor suppressor protein in superficial and invasive transitional cell bladder cancer: comparison with DNA ploidy.

doi:10.1016/S0090-4295(99)80216-7

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Article

Evaluation of overexpression of p53 tumor suppressor protein in superficial and invasive transitional cell bladder cancer: comparison with DNA ploidy.

Urology - 1 Sept 1995

Nakopoulou L, Constantinides C, Papandropoulos J, Theodoropoulos G, Tzonou A, Giannopoulos A, Zervas A, Dimopoulos C

Abstract excerpt

OBJECTIVES: p53 tumor suppressor gene is considered to play a significant role in carcinogenesis. Mutations in the p53 are the most frequent genetic abnormalities encountered in human malignancies. Our aim was to investigate the expression of p53 oncoprotein in superficial and invasive transitional cell bladder cancer (TCC) as well as its correlation with established prognostic factors, such as histologic grade,...

Topics

Adult
Aged
Aged, 80 and over
Aneuploidy
Carcinoma, Transitional Cell
DNA, Neoplasm
Female
Follow-Up Studies
Gene Expression
Genes, p53
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Mutation

Neoplasm Staging

Prognosis

Proportional Hazards Models

Survival Rate

Source

Open in PubMed

Identifiers

PMID: 7660508
DOI: 10.1016/S0090-4295(99)80216-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7660508-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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