Article
Immunohistochemical detection of p53 protein overexpression versus gene sequencing in urinary bladder carcinomas.
The Journal of urology - 1 Oct 1999
Bernardini S, Adessi G L, Billerey C, Chezy E, Carbillet J P, Bittard H
Abstract excerpt
PURPOSE: Mutations of p53 tumor suppressor gene and nuclear accumulation of p53 protein are common in bladder tumors. The prognostic significance of p53 alterations in bladder tumors has not been established. The aim of the present study was to evaluate an immunohistochemical (IHC) method for the routine determination of p53 protein overexpression in human bladder tumors and to determine the relation between...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
