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Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells.

Mutagenesis - 1 May 1994

Wang T S, Huang H

Abstract excerpt

The human carcinogen, arsenic, is genotoxic to mammalian cells in vitro. The mechanism is largely unknown, although the involvement of free radicals has been suggested. Since the X-ray sensitive Chinese hamster ovary cell line, XRS-5, is also sensitive to several free-radical generating agents, including H2O2, we have used this cell line to test whether the genotoxic effect of arsenite is mediated via the...

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Identifiers

PMID: 7934966
DOI: 10.1093/mutage/9.3.253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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