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Article

Short dysfunctional telomeres impair the repair of arsenite‐induced oxidative damage in mouse cells

11 Sept 2007

Abstract excerpt

Telomeres and telomerase appear to participate in the repair of broken DNA ends produced by oxidative damage. Arsenite is an environmental contaminant and a potent human carcinogen, which induces oxidative stress on cells via the generation of reactive oxygen species affecting cell viability and chromosome stability. It promotes telomere attrition and reduces cell survival by apoptosis. In this study, we used...

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Share to Advanced biosensing and bioanalysis techniques
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Share to Telomeres, Telomerase, and Senescence

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PMID: 17849448
DOI: 10.1002/jcp.21276

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